HPV- induced local epithelial hyperplasia.

ETIOLOGY

Caused by HPV-B and HPV-32

CLINICAL FEATURES

SEX- no gender prediliction

AGE- Children

SITE- labial, lingual, buccal mucosa.

clinical presentation

• LESION-
  • Papular in nature
  • broad based
  • same colour as skin-pale/white.

• 0.3-1 cm, discrete ,well demarcated plaques
• smooth surfaced/flat topped are commonly seen.
• they cluster closely together that they give COBBLE STONE/FISSURED APPEARANCE.

HISTOLOGIC FEATURES

• ACANTHOSIS of oral epithelium.
• RETE RIDGE FORMATION
  • normal
  • but are indented, confluent and club-shaped

• MITOSOID CELL
  • Result from viral alteration of the cells.

• PAPPILARY PROJECTIONS.

TREATMENT

• Conservative excisional biopsy.
• Spontaneous regression is observed.

A developmental anomaly characterized by heterotrophic collections of sebaceous glands at various sites in oral cavity.

ETIOLOGY

• Results from inclusion in oral cavity of ectoderm having some potentialities of skin in course of development of maxillary and mandibular process during embryonic life.

CLINICAL FEATURES

• SEX- no gender prediliction
• AGE- adults
• SITE- Oral mucosa

clinical presentation

• Small yellow spots either discreatly seperated/forming relatively large plaques-projecting slightly above the surface of the tissue.
• bilaterally symmetrical pattern.
• most common sites include-
  • oral mucosa
  • lips
  • retromolar area
  • tongue
  • gingiva
  • frenum
  • palate

HISTOLOGIC FEATURES

• Lobules of sebaceous duct beneath the epithelium.
• sebaceous cells are polygonal with centrally located nucleus and foamy cytoplasm.
• these sebaceous glands are unassociated with hair follicles.
• may show keratin plugging.

TREATMENT

No treatment is required.