Glucagon

About:

>Treats hypoglycaemia.
>Treats Severe bradycardia related to beta blockers.

Mode of action:

>29 Amino acid polypeptide.
>Secreted by pancreatic alpha cells.
>Stimulates hepatic gluconeogenesis.
>Only for those with hepatic glycogen.

Indications:

>Hypoglycaemia.
>Beta Blocker overdoseDoses.
>Adults 0.5-1 mg sc/iv/im.

Contraindications:

>Phaeochromocytoma.
>Cachexia and malnutrition - does not work as liver glycogen stores are depleted.

Side effects:

>Hyperglycaemia.

Reference:Tara V Shanbhag 3rd edition

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