• Mode of Action:  blocks K efflux (Class III antidysrhythmic); also has Na channel blocking (class I), beta blocking (class II), and Ca channel blocking (class IV) properties.
  • DOSE: Pulseless VF/VT: 300mg IV rapid push followed by 150mg IV rapid push if necessary at next pulse check.
  • Stable wide complex tachycardias: 150mg IV over 10 minutes, followed by infusion of 1mg/min x 6hours, then 0.5 mg/min thereafter.
  • EMERGENT INDICATIONS:  pulseless VF/VT, Wide complex tachydysrhythmias
  • WARNINGS:  Causes hypotension, prodysrhythmic, Preg D

Reference:PJ Mehta’s Practical Medicine .

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