it is also known as keratocystic odontogenic tumor ( KOT)






it is also known as keratocystic odontogenic tumor ( KOT)
also known as osteogenic sarcoma
A 35-year-old man presents with gross loosening of both his lower left premolar teeth. The gingiva around them looks swollen and is purple–brown in colour. A radiograph shows irregular bone destruction to the apices. Incisional biopsy shows multinucleated osteoclast-like giant cells in a haemorrhagic fibrous stroma.
Concepts of Health & Disease
Health is a basic human need and better health improves your quality of life.
There are various changing concepts of Health . Absence of disease being the traditional concept – Biomedical concept . Health is perceived in different ways nowadays giving rise to following concepts:
1. Biomedical concept
2.Ecological concept : Health is perceived as balance between man and his environment and one who cannot adjust is not fit to be called healthy.
3. Psychosocial concept : Health is also influenced by social, psychological , cultural , economic and political factors of the people concerned.
4.Holistic concept : is an integrated approach towards wellbeing of the human being.
This was keypoints about concepts of Health. I hope it helps .
A 60-year-old man has been treated for a T2N0M0 squamous-cell carcinoma by radical radiotherapy. He has a history of chronic alcoholism and was a heavy smoker. Six years after treatment, he develops a painful ulcer in the alveolar mucosa in the treated area following minor trauma. His pain worsens and the bone became progressively exposed. He is treated by a partial mandibular resection with graft.
A 58-year-old woman noticed that her front teeth had become spaced and seeks advice from her dentist. On entering the surgery, the dentist notices that she has difficulty in walking and does not respond to his questions. She has become increasingly deaf and her vision has also deteriorated. On examination, the maxilla and zygoma are enlarged and there is enlargement of the forehead.
1. What diagnosis would you suspect?
Pagetʼs disease of bone results in enlargement of cranial bones and deformation of weight- bearing bones. The cranium is usually expanded in thickness and symptoms may arise from cranial nerve compression.
2. What information might be gained from oral radiographs and blood tests to support this diagnosis?
Radiographs of the jaws may show hypercementosis, cemental masses, abnormal trabeculation and a cotton-wool appearance in the jaws. The alkaline phosphatase level is markedly raised.
3. What are the principal histological features of this disorder?
Disordered bone remodelling is seen; larger osteoclasts are present and the trabeculae show a scalloped outline. Numerous resting and reversal lines, resulting in a mosaic pattern, are seen and the vasculature may be increased. Globular cementum-like masses are seen in the jaws.